Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells

Hyposalivation often leads to irreversible and untreatable xerostomia. Salivary gland (SG) stem cell therapy is an attractive putative option to salvage these patients but is impeded by the limited availability of adult human tissue. Here, using murine SG cells, we demonstrate single-cell self-renew...

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Bibliographic Details
Main Authors: Lalitha S.Y. Nanduri, Mirjam Baanstra, Hette Faber, Cecilia Rocchi, Erik Zwart, Gerald de Haan, Ronald van Os, Robert P. Coppes
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003002