DNA Base Bioisosteres, Bis-benzoxazoles, Exert Anti-proliferative Effect on Human Prostate and Breast Cancer Cells

A series of symmetric bis-benzoxazole derivatives were synthesized using one-pot cyclisation reaction between 4-chloro substituted 2-aminophenol and suitable dicarboxylic acids. Synthesized compounds’ anticancer activities were tested by using MTT assay on human prostate (DU145) and breast (MCF7) ca...

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Bibliographic Details
Main Authors: Furkan Ayaz, Rusmeenee Kheeree, Qadar Ahmed Isse, Ronak Haj Ersan, Oztekin Algul
Format: Article
Language:English
Published: Turkish Chemical Society 2018-09-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
Online Access:http://dergipark.gov.tr/jotcsa/issue/37193/429504