LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

Abstract Background Long intergenic non-coding RNA 00963 (LINC00963) is an oncogenic lncRNA in human cancers. However, little is known on how it impacts the pathogenesis of lung adenocarcinoma (LUAD). Methods Biological effects on proliferation, migration, invasion, and epithelial-mesenchymal transi...

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Bibliographic Details
Main Authors: Ronghang Hu, Baobin Xu, Jiajun Ma, Linfeng Li, Liming Zhang, Li Wang, Jiebo Zhu, Tao Guo, Heng Zhang, Shaoqiang Wang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Medicine
Subjects:
Lung adenocarcinoma
LINC00963
HNRNPA2B1
Siah1
Zeb1
Exosomes
Online Access:https://doi.org/10.1186/s10020-022-00598-y

Internet

https://doi.org/10.1186/s10020-022-00598-y

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