Regional brain activation during rectal distention and attenuation with alosetron in a nonhuman primate model of irritable bowel syndrome

Abstract Greater understanding of the mechanism that mediates visceral pain and hypersensitivity associated with irritable bowel syndrome (IBS) would facilitate the development of effective therapeutics to manage these symptoms. An objective marker associated with the underlying mechanisms of viscer...

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Bibliographic Details
Main Authors: Rintaro Fujii, Yuji Awaga, Kenya Nozawa, Mayumi Matsushita, Aldric Hama, Takahiro Natsume, Hiroyuki Takamatsu
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2022-00048