Whole Body <i>Ip6k1</i> Deletion Protects Mice from Age-Induced Weight Gain, Insulin Resistance and Metabolic Dysfunction

Whole Body <i>Ip6k1</i> Deletion Protects Mice from Age-Induced Weight Gain, Insulin Resistance and Metabolic Dysfunction

(1) Background: We previously demonstrated that disruption of IP6K1 improves metabolism, protecting mice from high-fat diet-induced obesity, insulin resistance, and non-alcoholic fatty liver disease and steatohepatitis. Age-induced metabolic dysfunction is a major risk factor for metabolic diseases....

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Bibliographic Details
Main Authors: Sarbani Ghoshal, Sandip Mukherjee, Molee Chakraborty, Eliwaza Naomi Msengi, Jake Haubner, Anutosh Chakraborty
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
IP6K1
aging
metabolism
adipose tissue browning
weight gain
insulin resistance
Online Access:https://www.mdpi.com/1422-0067/23/4/2059

Internet

https://www.mdpi.com/1422-0067/23/4/2059

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