SLC6A4 Repeat and Single-Nucleotide Polymorphisms Are Associated With Depression and Rest Tremor in Parkinson's Disease: An Exploratory Study

SLC6A4 Repeat and Single-Nucleotide Polymorphisms Are Associated With Depression and Rest Tremor in Parkinson's Disease: An Exploratory Study

Introduction: Level of serotonin is mainly regulated by the serotonin reuptake transporter encoded by SLC6A4. The promoter region of SLC6A4 bears a repeat polymorphism 5-HTTLPR and a single nucleotide polymorphism rs25531. We have previously studied the association between these two variants and spo...

Full description

Bibliographic Details
Main Authors: Jian-Yong Wang, Qian-Ya Fan, Jia-Hui He, Shi-Guo Zhu, Chen-Ping Huang, Xiong Zhang, Jian-Hong Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
serotonin reuptake transporter
SLC6A4
depression
tremor
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00333/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00333/full

Similar Items