S100A8 promotes epithelial‐mesenchymal transition and metastasis under TGF‐β/USF2 axis in colorectal cancer

S100A8 promotes epithelial‐mesenchymal transition and metastasis under TGF‐β/USF2 axis in colorectal cancer

Abstract Background The transforming growth factor‐β (TGF‐β) pathway plays a pivotal role in inducing epithelial‐mesenchymal transition (EMT), which is a key step in cancer invasion and metastasis. However, the regulatory mechanism of TGF‐β in inducing EMT in colorectal cancer (CRC) has not been ful...

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Bibliographic Details
Main Authors: Si Li, Jun Zhang, Senmi Qian, Xuesong Wu, Liang Sun, Tianyi Ling, Yao Jin, Wenxiao Li, Lichao Sun, Maode Lai, Fangying Xu
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Cancer Communications
Subjects:
colorectal cancer
epithelial‐mesenchymal transition
metastasis
prognosis
transforming growth factor‐β
upstream transcription factor 2
Online Access:https://doi.org/10.1002/cac2.12130

Internet

https://doi.org/10.1002/cac2.12130

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