Interleukin-34 Enhances the Tumor Promoting Function of Colorectal Cancer-Associated Fibroblasts

The stromal compartment of colorectal cancer (CRC) is marked by the presence of large numbers of fibroblasts, termed cancer-associated fibroblasts (CAFs), which promote CRC growth and progression through the synthesis of various molecules targeting the neoplastic cells. Interleukin (IL)-34, a cytoki...

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Bibliographic Details
Main Authors: Eleonora Franzè, Antonio Di Grazia, Giuseppe Sigismondo Sica, Livia Biancone, Federica Laudisi, Giovanni Monteleone
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/12/3537