PRDX6 Protects ARPE-19 Cells from Oxidative Damage via PI3K/AKT Signaling

PRDX6 Protects ARPE-19 Cells from Oxidative Damage via PI3K/AKT Signaling

Background/Aims: Oxidative stress that damages cells of the retinal pigment epithelium (RPE) can cause the development of hereditary retinal disease (HRD). PRDX6, which is a member of the PRDX family, is essential for removing metabolic free radicals from the body. However, the effect of PRDX6 on ox...

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Bibliographic Details
Main Authors: Xu Zha, Guojiu Wu, Xueying Zhao, Liqiong Zhou, Hong Zhang, Jinghua Li, Linkun Ma, Yuanping Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
ARPE-19
PRDX6
Oxidative stress
Apoptosis
PI3K/AKT signaling pathway
Online Access:http://www.karger.com/Article/FullText/430186

Internet

http://www.karger.com/Article/FullText/430186

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