Crosstalk between tumour and stroma modifies CLIC4 cargo in extracellular vesicles
Abstract Mouse models of breast cancer have revealed that tumour‐bearing hosts must express the oxidoreductase CLIC4 to develop lung metastases. In the absence of host CLIC4, primary tumours grow but the lung premetastatic niche is defective for metastatic seeding. Primary breast cancer cells releas...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-10-01
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Series: | Journal of Extracellular Biology |
Subjects: | |
Online Access: | https://doi.org/10.1002/jex2.118 |