Crosstalk between tumour and stroma modifies CLIC4 cargo in extracellular vesicles

Abstract Mouse models of breast cancer have revealed that tumour‐bearing hosts must express the oxidoreductase CLIC4 to develop lung metastases. In the absence of host CLIC4, primary tumours grow but the lung premetastatic niche is defective for metastatic seeding. Primary breast cancer cells releas...

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Bibliographic Details
Main Authors: Vanesa C. Sanchez, Alayna Craig‐Lucas, Christophe Cataisson, Brandi L. Carofino, Stuart H. Yuspa
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Journal of Extracellular Biology
Subjects:
Online Access:https://doi.org/10.1002/jex2.118