Rescue of follicle development after oocyte-induced ovary dysfunction and infertility in a model of POI

The mechanisms and aetiology underlying the development of premature ovarian insufficiency (POI) are poorly understood. However, the oocyte clearly has a role as demonstrated by the Double Mutant (DM) mouse model where ovarian dysfunction (6 weeks) is followed by POI (3 months) due to oocyte-specifi...

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Bibliographic Details
Main Authors: Sairah Sheikh, Belinda K. M. Lo, Heidy Kaune, Jassimran Bansal, Anna Deleva, Suzannah A. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1202411/full