Attenuation of Zika Virus by Passage in Human HeLa Cells

Attenuation of Zika Virus by Passage in Human HeLa Cells

Zika virus (ZIKV) is a mosquito-borne Flavivirus. Previous studies have shown that mosquito-transmitted flaviviruses, including yellow fever, Japanese encephalitis, and West Nile viruses, could be attenuated by serial passaging in human HeLa cells.  Therefore, it was hypothesized that wild-...

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Bibliographic Details
Main Authors: Li Li, Natalie D. Collins, Steven G. Widen, Emily H. Davis, Jaclyn A. Kaiser, Mellodee M. White, M. Banks Greenberg, Alan D.T. Barrett, Nigel Bourne, Vanessa V. Sarathy
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Vaccines
Subjects:
Zika virus
attenuation
flavivirus
HeLa cells
Zika virus prM
Zika virus NS1
Online Access:https://www.mdpi.com/2076-393X/7/3/93

Internet

https://www.mdpi.com/2076-393X/7/3/93

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