Epithelial uptake leads to fungal killing in vivo and is aberrant in COPD-derived epithelial cells

Summary: Hundreds of spores of Aspergillus fumigatus (Af) are inhaled daily by human beings, representing a constant, possibly fatal, threat to respiratory health. The small size of Af spores suggests that interactions with alveolar epithelial cells (AECs) are frequent; thus, we hypothesized that sp...

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Détails bibliographiques
Auteurs principaux: Margherita Bertuzzi, Gareth J. Howell, Darren D. Thomson, Rachael Fortune-Grant, Anna Möslinger, Patrick Dancer, Norman Van Rhijn, Natasha Motsi, Alice Codling, Elaine M. Bignell
Format: Article
Langue:English
Publié: Elsevier 2024-06-01
Collection:iScience
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2589004224011611