Regulated intramembrane proteolysis, innate immunity and therapeutic targets in Alzheimer’s disease
The critical discovery of the presenilins and their association with familial Alzheimer’s disease (AD) prompted an intensive research effort to understand the molecular mechanisms of that disease. The presenilins were subsequently found to be the catalytic component of the multi-protein enzyme compl...
Main Authors: | Caroline Coleman-Vaughan, Indu Patwal, Justin V. McCarthy, Tara P. Hurst |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2016-04-01
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Series: | AIMS Molecular Science |
Subjects: | |
Online Access: | http://www.aimspress.com/Molecular/article/749/fulltext.html |
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