Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus

DNA methylation is an epigenetic mechanism important for the regulation of gene expression, which plays a vital role in the interaction between genetic and environmental factors. Aberrant epigenetic changes are implicated in the pathogenesis of diabetes and diabetic complications, but the role of DN...

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Bibliographic Details
Main Authors: Kai Guo, Sarah Elzinga, Stephanie Eid, Claudia Figueroa-Romero, Lucy M. Hinder, Crystal Pacut, Eva L. Feldman, Junguk Hur
Format: Article
Language:English
Published: Taylor & Francis Group 2019-08-01
Series:Epigenetics
Subjects:
type 2 diabetes
diabetic peripheral neuropathy
dna methylation
reduced representation bisulfite sequencing
rrbs
Online Access:http://dx.doi.org/10.1080/15592294.2019.1615352

Internet

http://dx.doi.org/10.1080/15592294.2019.1615352

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