A Novel Protein Encoded by Exosomal CircATG4B Induces Oxaliplatin Resistance in Colorectal Cancer by Promoting Autophagy

Abstract Oxaliplatin is commonly used in chemotherapeutic regimens for colorectal cancer (CRC) after surgical resection. However, acquired chemoresistance seriously affects the curative effect in CRC patients, and the mechanism is still unclear. Here, a circular RNA, circATG4B is identified, which p...

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Bibliographic Details
Main Authors: Zihao Pan, Jun Zheng, Jiebin Zhang, Jiatong Lin, Jianguo Lai, Zejian Lyu, Huolun Feng, Junjiang Wang, Deqing Wu, Yong Li
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202204513