The Impacts of Method Selectivity and Binders on the Properties of Carbamazepine Granules and Their Applications: A Case Study

Background: Carbamazepine (CBZ) is a BCS II class drug, having many challenges in solubility, flowability, and compactibility. The study focused on the improvement of solubility, flow behavior, and drug release of carbamazepine. Methods: Low shear granulation (LSG), extrusion spheronization (ES), hi...

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Bibliographic Details
Main Authors: Rahul Tatyarao Shete, Bhaskar Narayan Thorat, Purnima Dhanraj Amin
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-07-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-28-459.pdf