Inborn Errors in the LRR Domain of Nod2 and Their Potential Consequences on the Function of the Receptor
The innate immune system plays a critical role in the early detection of pathogens, primarily by relying on pattern-recognition receptor (PRR) signaling molecules. Nucleotide-binding oligomerization domain 2 (NOD2) is a cytoplasmic receptor that recognizes invading molecules and danger signals insid...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/8/2031 |