Hypoxia-induced therapy resistance: Available hypoxia-targeting strategies and current advances in head and neck cancer

Most solid tumors, such as head and neck cancers, feature a hypoxic microenvironment due to angiogenic dysregulation and the consequent disruption of their vascular network. Such nutrient-deprived environment can induce genomic changes in several tumor cell populations, conferring survival and proli...

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Bibliographic Details
Main Authors: Victoria L. Codony, Mahvash Tavassoli
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000097