Suppression of virus specific immune responses by IL-10 in acute dengue infection.

Suppression of virus specific immune responses by IL-10 in acute dengue infection.

Elevated IL-10 has been shown to be associated with severe dengue infection (DI). We proceeded to investigate the role of IL-10 in the pathogenesis of acute DI.Ex vivo and cultured IFNγ ELISpot assays for dengue virus (DENV) NS3 protein and non dengue viral proteins were carried out in 26 patients w...

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Bibliographic Details
Main Authors: Gathsaurie Neelika Malavige, Chandima Jeewandara, K M Luckmaal Alles, Maryam Salimi, Laksiri Gomes, Achala Kamaladasa, S D Jayaratne, Graham Stuart Ogg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3764236?pdf=render

Internet

http://europepmc.org/articles/PMC3764236?pdf=render

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