A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

There is an urgent need to develop new methods for male contraception, however a major barrier to drug discovery has been the lack of validated targets and the absence of an effective high-throughput phenotypic screening system. To address this deficit, we developed a fully-automated robotic screeni...

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Bibliographic Details
Main Authors: Franz S Gruber, Zoe C Johnston, Christopher LR Barratt, Paul D Andrews
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/51739