CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes

CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes

Objective: Modic changes (MC) are vertebral bone marrow lesions seen on magnetic resonance images, that associate with disc degeneration and low back pain (LBP). Few studies described MC histopathology qualitatively based on a few patient samples. CD90-positive bone marrow stromal cells were shown t...

Full description

Bibliographic Details
Main Authors: Stefan Dudli, Agnieszka Karol, Luca Giudici, Irina Heggli, Christoph J Laux, Jose M Spirig, Florian Wanivenhaus, Michael Betz, Christoph Germann, Nadja Farshad-Amacker, Florian Brunner, Oliver Distler, Mazda Farshad
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Low back pain
Modic changes
Bone marrow oedema
Fibrosis
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913122000553

Internet

http://www.sciencedirect.com/science/article/pii/S2665913122000553

Similar Items