CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes

Objective: Modic changes (MC) are vertebral bone marrow lesions seen on magnetic resonance images, that associate with disc degeneration and low back pain (LBP). Few studies described MC histopathology qualitatively based on a few patient samples. CD90-positive bone marrow stromal cells were shown t...

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Hlavní autoři: Stefan Dudli, Agnieszka Karol, Luca Giudici, Irina Heggli, Christoph J Laux, Jose M Spirig, Florian Wanivenhaus, Michael Betz, Christoph Germann, Nadja Farshad-Amacker, Florian Brunner, Oliver Distler, Mazda Farshad
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2022-09-01
Edice:Osteoarthritis and Cartilage Open
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2665913122000553