Protective effects and mechanisms of N-acetylcysteine on indomethacin-induced intestinal injury in a porcine model

Protective effects and mechanisms of N-acetylcysteine on indomethacin-induced intestinal injury in a porcine model

This study aimed to investigate the effect of N-acetylcysteine (NAC) on indomethacin (IDMT)-induced intestinal injury in a piglet model and explore the underlying molecular mechanisms. Piglets were randomly divided into 3 treatment groups: (1) control group; (2) IDMT group; (3) NAC+IDMT group. The r...

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Bibliographic Details
Main Authors: Qian Zhang, Wenkai Liu, Qian Li, Yitong Zeng, Mengjun Wu, Tao Wu, Shuangshuang Guo, Lei Wang, Di Zhao, Dan Yi, Yongqing Hou
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
N-acetylcysteine
Indomethacin
Intestines
Antioxidants
Anti-inflammatory
Arginine
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323006772

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http://www.sciencedirect.com/science/article/pii/S0147651323006772

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