Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues

Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues

Abstract Immune profiling is becoming a vital tool for identifying predictive and prognostic markers for translational studies. The study of the tumor microenvironment (TME) in paraffin tumor tissues such as malignant pleural mesothelioma (MPM) could yield insights to actionable targets to improve p...

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Bibliographic Details
Main Authors: Edwin R. Parra, Jie Zhai, Auriole Tamegnon, Nicolas Zhou, Renganayaki Krishna Pandurengan, Carmelia Barreto, Mei Jiang, David C. Rice, Caitlin Creasy, Ara A. Vaporciyan, Wayne L. Hofstetter, Anne S. Tsao, Ignacio I. Wistuba, Boris Sepesi, Cara Haymaker
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83858-x

Internet

https://doi.org/10.1038/s41598-021-83858-x

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