SHP2 potentiates anti-PD-1 effectiveness through intervening cell pyroptosis resistance in triple-negative breast cancer
Triple negative breast cancer (TNBC) presents a formidable challenge due to the lack of effective treatment modalities. Immunotherapy stands as a promising therapeutic approach; however, the emergence of drug resistance mechanisms within tumor cells, particularly those targeting apoptosis and pyropt...
Main Authors: | Chao Chen, Yuanyuan Cheng, Haoqi Lei, Xuefei Feng, Hongxia Zhang, Lingling Qi, Jufeng Wan, Haiying Xu, Xin Zhao, Yan Zhang, Baofeng Yang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332223015950 |
Similar Items
-
Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors
by: Zhen Dai, et al.
Published: (2023-05-01) -
The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro
by: Jiaqiao Zhu, et al.
Published: (2023-01-01) -
Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
by: Xiaozheng Xu, et al.
Published: (2021-11-01) -
TSPO Deficiency Exacerbates GSDMD-Mediated Macrophage Pyroptosis in Inflammatory Bowel Disease
by: Xue Zhang, et al.
Published: (2022-03-01) -
Curcumin activates NLRC4, AIM2, and IFI16 inflammasomes and induces pyroptosis by up-regulated ISG3 transcript factor in acute myeloid leukemia cell lines
by: Yuru Zhou, et al.
Published: (2022-12-01)