The preventive effects of ascorbic acid supplementation on locomotor and acetylcholinesterase activity in an animal model of schizophrenia induced by ketamine

ABSTRACT Studies have shown that schizophrenic patients seem to have nutritional deficiencies. Ascorbic acid (AA) has an important antioxidant effect and neuromodulatory properties. The aim of this study was to evaluate the effects of AA on locomotor activity and the acetylcholinesterase activity (A...

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Main Authors: LOUYSE S. DAMAZIO, FLÁVIA R. SILVEIRA, LARA CANEVER, ADALBERTO A. DE CASTRO, JADNE M. ESTRELA, JOSIANE BUDNI, ALEXANDRA I. ZUGNO
Format: Article
Language:English
Published: Academia Brasileira de Ciências
Series:Anais da Academia Brasileira de Ciências
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017005009104&lng=en&tlng=en