Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that is able to infect fibroblastic, epithelial, endothelial and hematopoietic cells. Over the past ten years, several groups have provided direct evidence that dendritic cells (DCs) fully support the HCMV lytic cycle. We previously demonstrat...

Full description

Bibliographic Details
Main Authors: Fabienne Haspot, Amélie Lavault, Christian Sinzger, Kerstin Laib Sampaio, York-Dieter Stierhof, Paul Pilet, Céline Bressolette-Bodin, Franck Halary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3322158?pdf=render