Study of the mechanism by gentiopicroside protects against skin fibroblast glycation damage via the RAGE pathway

Study of the mechanism by gentiopicroside protects against skin fibroblast glycation damage via the RAGE pathway

Abstract The occurrence of nonenzymatic glycosylation reactions in skin fibroblasts can lead to severe impairment of skin health. To investigate the protective effects of the major functional ingredient from Gentianaceae, gentiopicroside (GPS) on fibroblasts, network pharmacology was used to analyse...

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Bibliographic Details
Main Authors: Chunyu Chen, Xiaoxing Liu, Li Li, Miaomiao Guo, Yifan He, Yinmao Dong, Hong Meng, Fan Yi
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Gentiopicroside
Glycosylation
AGE inhibitor
RAGE
Online Access:https://doi.org/10.1038/s41598-024-55525-4

Internet

https://doi.org/10.1038/s41598-024-55525-4

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