The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis

Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24.

Bibliographic Details
Main Authors: Shuo Geng, Keqiang Chen, Ruoxi Yuan, Liang Peng, Urmila Maitra, Na Diao, Chun Chen, Yao Zhang, Yuan Hu, Chen-Feng Qi, Susan Pierce, Wenhua Ling, Huabao Xiong, Liwu Li
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13436