The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
Chronic low-grade inflammation has been suspected to promote atherosclerosis. Here, Geng et al. show that sustained low-grade inflammation promotes atherosclerosis in mice via monocyte programing that involves a coupled disruption of IRAK-M regulation and induction of miR-24.
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13436 |