Nucleocapsid protein-based vaccine provides protection in mice against lethal Crimean-Congo hemorrhagic fever virus challenge.

Crimean-Congo hemorrhagic fever (CCHF) is an acute, often fatal viral disease characterized by rapid onset of febrile symptoms followed by hemorrhagic manifestations. The etiologic agent, CCHF orthonairovirus (CCHFV), can infect several mammals in nature but only seems to cause clinical disease in h...

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Bibliographic Details
Main Authors: Marko Zivcec, David Safronetz, Dana P Scott, Shelly Robertson, Heinz Feldmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6062107?pdf=render