Compartmentalised RNA catalysis in membrane-free coacervate protocells

Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequestering RNA based on length.

Manylion Llyfryddiaeth
Prif Awduron: Björn Drobot, Juan M. Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Nature Portfolio 2018-09-01
Cyfres:Nature Communications
Mynediad Ar-lein:https://doi.org/10.1038/s41467-018-06072-w