Transcription factor p73 regulates Th1 differentiation

Heterogeneous helper T (Th) cell responses contribute to differential susceptibility to immunological disorders. Here the authors perform haplotype-based computational screens of 16 inbred mouse strains to identify a transcription factor, p73, as an important negative regulator of Th1 differentiatio...

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Bibliographic Details
Main Authors: Min Ren, Majid Kazemian, Ming Zheng, JianPing He, Peng Li, Jangsuk Oh, Wei Liao, Jessica Li, Jonathan Rajaseelan, Brian L. Kelsall, Gary Peltz, Warren J. Leonard
Format: Article
Language:English
Published: Nature Portfolio 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15172-5