The CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial

The CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial

Abstract Background Familial adenomatous polyposis (FAP) is a rare autosomal dominant disease characterized by germline mutations in the Adenomatous Polyposis Coli (APC) gene, resulting in the development of numerous colorectal adenomas. As these patients have a high risk of developing colorectal ca...

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Bibliographic Details
Main Authors: Jasmijn D. G. Linssen, Sanne M. van Neerven, Arthur S. Aelvoet, Clara C. Elbers, Louis Vermeulen, Evelien Dekker
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Gastroenterology
Subjects:
Chemoprevention
Colorectal adenomas
Familial adenomatous polyposis
Lithium carbonate
Online Access:https://doi.org/10.1186/s12876-022-02442-3

Internet

https://doi.org/10.1186/s12876-022-02442-3

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