The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells—A Systematic Analysis

The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells—A Systematic Analysis

Cyclin-dependent kinase inhibitors (CDKi´s) display cytotoxic activity against different malignancies, including head and neck squamous cell carcinomas (HNSCC). By coordinating the DNA damage response, these substances may be combined with cytostatics to enhance cytotoxicity. Here, we investigated t...

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Bibliographic Details
Main Authors: Nina Schoenwaelder, Inken Salewski, Nadja Engel, Mareike Krause, Björn Schneider, Michael Müller, Christin Riess, Heiko Lemcke, Anna Skorska, Christina Grosse-Thie, Christian Junghanss, Claudia Maletzki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
targeted therapy
combination strategies
immunogenic cell death
xenograft model
Online Access:https://www.mdpi.com/2072-6694/13/10/2396

Internet

https://www.mdpi.com/2072-6694/13/10/2396

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