Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types

Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types

The system (PTTRS) formed by typical 2-Cys peroxiredoxins (Prx), thioredoxin (Trx), Trx reductase (TrxR), and sulfiredoxin (Srx) is central in antioxidant protection and redox signaling in the cytoplasm of eukaryotic cells. Understanding how the PTTRS integrates these functions requires tracing phen...

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Bibliographic Details
Main Authors: Gianluca Selvaggio, Pedro M.B.M. Coelho, Armindo Salvador
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
Redox relays
Redox signaling
Thiol redox regulation
Quantitative redox biology
Systems design space methodology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717308819

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http://www.sciencedirect.com/science/article/pii/S2213231717308819

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