LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis

Abstract Long noncoding RNAs (lncRNAs) are involved in diabetes related diseases. However, the role of lncRNAs in the pathogenesis of type 2 diabetes with macrovascular complication (DMC) has seldomly been recognized. This study screened lncRNA profiles of leukocytes from DMC patients and explored p...

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Bibliographic Details
Main Authors: Xiao Zhu, Yihan Liu, Jia Cui, Jianyi Lv, Changlong Li, Jing Lu, Xueyun Huo, Jingtao Dou, Zhigang Bai, Zhenwen Chen, Xiaoyan Du
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01019-z