Strand asymmetry influences mismatch resolution during a single-strand annealing

Abstract Background Biases of DNA repair can shape the nucleotide landscape of genomes at evolutionary timescales. The molecular mechanisms of those biases are still poorly understood because it is difficult to isolate the contributions of DNA repair from those of DNA damage. Results Here, we develo...

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Bibliographic Details
Main Authors: Victoria O. Pokusaeva, Aránzazu Rosado Diez, Lorena Espinar, Albert Torelló Pérez, Guillaume J. Filion
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-022-02665-3