The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

<p>Abstract</p> <p>Background</p> <p>Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further explore these effects we ha...

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Bibliographic Details
Main Authors: Eriksen Erik F, Waarsing Jan H, Fossmark Reidar, Gustafsson Björn I, Westbroek Irene, Stunes Astrid K, Petzold Christiane, Reseland Janne E, Syversen Unni
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Endocrine Disorders
Online Access:http://www.biomedcentral.com/1472-6823/11/11

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http://www.biomedcentral.com/1472-6823/11/11

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