Targeting GSTP1-dependent ferroptosis in lung cancer radiotherapy: Existing evidence and future directions

Radiotherapy is applied in about 70% patients with tumors, yet radioresistance of tumor cells remains a challenge that limits the efficacy of radiotherapy. Ferroptosis, an iron-dependent lipid peroxidation regulated cell death, is involved in the development of a variety of tumors. Interestingly, th...

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Bibliographic Details
Main Authors: Xin Tan, Xiang Huang, Baolong Niu, Xingdong Guo, Xiao Lei, Baolin Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1102158/full