Radiation Induces Distinct Changes in Defined Subpopulations of Neural Stem and Progenitor Cells in the Adult Hippocampus

Radiation Induces Distinct Changes in Defined Subpopulations of Neural Stem and Progenitor Cells in the Adult Hippocampus

While irradiation can effectively treat brain tumors, this therapy also causes cognitive impairments, some of which may stem from the disruption of hippocampal neurogenesis. To study how radiation affects neurogenesis, we combine phenotyping of subpopulations of hippocampal neural stem and progenito...

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Bibliographic Details
Main Authors: Olga A. Mineyeva, Dmitri V. Bezriadnov, Alexander V. Kedrov, Alexander A. Lazutkin, Konstantin V. Anokhin, Grigori N. Enikolopov
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
adult neurogenesis
stem cells
quiescent progenitors
gamma irradiation
nucleotide labeling
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.01013/full

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https://www.frontiersin.org/article/10.3389/fnins.2018.01013/full

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