Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors

Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors

<i>Background</i>: The up-regulation of a telomere maintenance mechanism (TMM) is a common feature of cancer cells and a hallmark of cancer. Routine methods for detecting TMMs in tumor samples are still missing, whereas telomerase targeting treatments are becoming available. In paediatri...

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Bibliographic Details
Main Authors: Aurora Irene Idilli, Francesca Pagani, Emanuela Kerschbamer, Francesco Berardinelli, Manuel Bernabé, María Luisa Cayuela, Silvano Piazza, Pietro Luigi Poliani, Emilio Cusanelli, Maria Caterina Mione
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
pediatric brain tumors
ALT
telomere maintenance mechanisms
pre-replicative complex
heterochromatin
zebrafish
Online Access:https://www.mdpi.com/2072-6694/12/4/1028

Internet

https://www.mdpi.com/2072-6694/12/4/1028

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