TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1

TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1

Sepsis is a common complication of infections that significantly impacts the survival of critically patients. Currently, effective pharmacological treatment strategies are lacking. Auranofin, known as an inhibitor of Thioredoxin reductase (TrxR), exhibits anti-inflammatory activity, but its role in...

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Bibliographic Details
Main Authors: Dongsheng Bai, Chen Zhou, Jiaying Du, Jiawei Zhao, Chunyang Gu, YuXiang Wang, Lulu Zhang, Na Lu, Yue Zhao
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Redox Biology
Subjects:
TrxR
Thioredoxin-1
Caveolin-1
Outer membrane vesicle
Caspase-11
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724002556

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http://www.sciencedirect.com/science/article/pii/S2213231724002556

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