Designing nanostructured lipid carriers modified with folate-conjugated chitosan for targeted delivery of osthole to HT-29 colon cancer cells: investigation of anticancer, antioxidant, and antibacterial activities

Abstract The present study proposed to design nanostructured lipid carriers (NLC) coated with chitosan (CS) conjugated folate (FA) for the targeted delivery of Osthole (OST) to the HT-29 colon cancer cell line and improve its anticancer capability. To assess the physicochemical characteristics of OS...

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Bibliographic Details
Main Authors: Ghazal Hosseini Torshizi, Masoud Homayouni Tabrizi, Ehsan Karimi, Atefeh Younesi, Zahra Larian
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cancer Nanotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12645-024-00246-6