Detection of Ras nanoclustering-dependent homo-FRET using fluorescence anisotropy measurements
The small GTPase Ras is frequently mutated in cancer and a driver of tumorigenesis. The recent years have shown great progress in drug-targeting Ras and understanding how it operates on the plasma membrane. We now know that Ras is non-randomly organized into proteo-lipid complexes on the membrane, c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | European Journal of Cell Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0171933523000298 |