Detection of Ras nanoclustering-dependent homo-FRET using fluorescence anisotropy measurements

The small GTPase Ras is frequently mutated in cancer and a driver of tumorigenesis. The recent years have shown great progress in drug-targeting Ras and understanding how it operates on the plasma membrane. We now know that Ras is non-randomly organized into proteo-lipid complexes on the membrane, c...

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Bibliographic Details
Main Authors: Ganesh babu Manoharan, Camilo Guzmán, Arafath Kaja Najumudeen, Daniel Abankwa
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000298