Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model

Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model

Abstract Background Necrotizing enterocolitis (NEC) is a leading cause of death in preterm infants. Neonates weighing <1500 grams are at the highest risk for acquiring NEC, with a prevalence of nearly 7-10%, mortality up to 30%, and several long-term complications among survivors. Despite advance...

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Bibliographic Details
Main Authors: Srikanth Ravisankar, Rodney Tatum, Parvesh M. Garg, Maja Herco, Prem S. Shekhawat, Yan-Hua Chen
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Pediatrics
Subjects:
Necrotizing enterocolitis
Tight junctions
Claudin proteins
Biotin tracer molecules
Epithelial barrier function
Online Access:http://link.springer.com/article/10.1186/s12887-018-1346-x

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http://link.springer.com/article/10.1186/s12887-018-1346-x

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