Metagenomic versus targeted next-generation sequencing for detection of microorganisms in bronchoalveolar lavage fluid among renal transplantation recipients

Metagenomic versus targeted next-generation sequencing for detection of microorganisms in bronchoalveolar lavage fluid among renal transplantation recipients

BackgroundMetagenomic next-generation sequencing (mNGS), which provides untargeted and unbiased pathogens detection, has been extensively applied to improve diagnosis of pulmonary infection. This study aimed to compare the clinical performance between mNGS and targeted NGS (tNGS) for microbial detec...

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Bibliographic Details
Main Authors: Zhaoru Huang, Bingxue Hu, Jinfeng Li, Min Feng, Zhigang Wang, Fengxiang Huang, Huan Xu, Lei Liu, Wenjun Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
pulmonary infection
metagenomics Next-Generation Sequencing (mNGS)
targeted next-generation sequencing (tNGS)
respiratory pathogens
Torque teno virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1443057/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1443057/full

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