Central and peripheral analgesic active components of triterpenoid saponins from Stauntonia chinensis and their action mechanism

Central and peripheral analgesic active components of triterpenoid saponins from Stauntonia chinensis and their action mechanism

Triterpenoid saponins from Stauntonia chinensis have been proven to be a potential candidate for inflammatory pain relief. Our pharmacological studies confirmed that the analgesic role of triterpenoid saponins from S. chinensis occurred via a particular increase in the inhibitory synaptic response i...

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Bibliographic Details
Main Authors: Ji-Hong Gong, Chang-Ming Zhang, Bo Wu, Zi-Xun Zhang, Zhong-Yan Zhou, Jia-Hui Zhu, Han Liu, Yi Rong, Qian Yin, Ya-Ting Chen, Rong Zheng, Guang-Zhong Yang, Xiao-Fei Yang, Su Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
stauntonia chinensis
triterpenoid saponins
analgesia
neural signal transduction
transient receptor potential vanilloid 1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1275041/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1275041/full

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