Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cells.

Human primary myotubes are highly glycolytic when cultured in high glucose medium rendering it difficult to study mitochondrial dysfunction. Galactose is known to enhance mitochondrial metabolism and could be an excellent model to study mitochondrial dysfunction in human primary myotubes. The aim of...

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Bibliographic Details
Main Authors: Céline Aguer, Daniela Gambarotta, Ryan J Mailloux, Cynthia Moffat, Robert Dent, Ruth McPherson, Mary-Ellen Harper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3240634?pdf=render